Bioactive Compound Details
| Compound ID: | B143589 |
| Source ID: | CHEMBL565 |
| Source Type: | Small molecule |
| Compound Name: | CLOFIBRATE |
| Synonyms: | ATROMID-S|AY-61123|Atromid|CHLORFENISATE|CLOFIBRATE|ETHYL P-CHLOROPHENOXYISOBUTYRATE|ICI 28257|ICI-28257|NSC-79389 |
| Molecular Formula: | C12H15ClO3 |
| SMILES: | CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T03 | Peroxisome proliferator-activated receptor alpha | PPARA | agonist | Nuclear hormone receptor | Q07869 | PPARA_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |