Bioactive Compound Details
| Compound ID: | B143641 |
| Source ID: | CHEMBL566534 |
| Source Type: | Small molecule |
| Compound Name: | ARTEMETHER |
| Synonyms: | .BETA.-ARTEMETHER|ARTEMETHER|ARTEMETHERUM|ARTESAPH|Artemetheri|DIHYDROARTEMISININ IMPURITY G|FALCIDOL|GVITHER|LARITHER|MALARTEM|NSC-665970|NSC-759820|PALUTHER|SM 224 |
| Molecular Formula: | C16H26O5 |
| SMILES: | CO[C@H]1O[C@@H]2O[C@@]3(C)CC[C@H]4[C@H](C)CC[C@@H]([C@H]1C)[C@]42OO3 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |