Bioactive Compound Details
| Compound ID: | B144934 |
| Source ID: | CHEMBL614 |
| Source Type: | Small molecule |
| Compound Name: | PYRAZINAMIDE |
| Synonyms: | .ALPHA.-PYRAZINAMIDE|ALDINAMID|ALDINAMIDE|D-50|EPRAZIN|FARMIZINA|ISOPAS|MK-56|NOVAMID|NSC-14911|PIRAZIMIDA|PIRAZINAMID|PIRILENE|PYRAFAT|PYRAMIZADE|PYRAZIDE|PYRAZINAMIDE|PYRAZINAMIDUM|PYRAZINE CARBOXYLAMIDE|PYRAZINECARBOXAMIDE|Pyrazinamide|ROZIDE|TEBRAZID|UNIPYRANAMIDE|ZINAMIDE |
| Molecular Formula: | C5H5N3O |
| SMILES: | NC(=O)c1cnccn1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |