Bioactive Compound Details
| Compound ID: | B144954 |
| Source ID: | CHEMBL622 |
| Source Type: | Small molecule |
| Compound Name: | ETODOLAC |
| Synonyms: | (RS)-ETODOLIC ACID|AY-24,236|AY-24-236|AY-24236|EBRETIN|ECCOXOLAC|EDOLAN|ETODOLAC|ETODOLIC ACID|ETOLYN|ETOPAN XL|FLANCOX|LODIN XL|LODINE SR|LODINE XL|Lodine|NAPILAC|NIH-9918|NSC-282126|RAMODAR|TEDOLAN|ULTRADOL|ZEDOLAC |
| Molecular Formula: | C17H21NO3 |
| SMILES: | CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)O)OCC3 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |