Bioactive Compound Details
| Compound ID: | B144961 |
| Source ID: | CHEMBL625 |
| Source Type: | Small molecule |
| Compound Name: | THIABENDAZOLE |
| Synonyms: | E233|Equizole|LOMBRISTOP|MINZOLUM|MK-360|Mintezol|NEMAPAN|NSC-525040|NSC-90507|OMNIZOLE|Omnizole|PITRIZET|THIABENDAZOLE|THIABENZOLE|TIABENDAZOLE|Tiabendazole |
| Molecular Formula: | C10H7N3S |
| SMILES: | c1ccc2[nH]c(-c3cscn3)nc2c1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |