Bioactive Compound Details
| Compound ID: | B144974 |
| Source ID: | CHEMBL632 |
| Source Type: | Small molecule |
| Compound Name: | BETAMETHASONE |
| Synonyms: | ALPHATREX|BETA-VAL|BETAMETHASONE|BETNELAN|Betasolan|Betatrex|Celestone|Dermabet|FLUBENISOLONE|Lotrisone|NSC-39470|SCH 4831|SCH-4831|Taclonex|Uticort|VISUBETA |
| Molecular Formula: | C22H29FO5 |
| SMILES: | C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |