Bioactive Compound Details
| Compound ID: | B144976 |
| Source ID: | CHEMBL63323 |
| Source Type: | Small molecule |
| Compound Name: | NIFLUMIC ACID |
| Synonyms: | NIFLUGEL|NIFLUMIC ACID|NSC-758196|UP 83|UP-83 |
| Molecular Formula: | C13H9F3N2O2 |
| SMILES: | O=C(O)c1cccnc1Nc1cccc(C(F)(F)F)c1 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |