Bioactive Compound Details
| Compound ID: | B144979 |
| Source ID: | CHEMBL635 |
| Source Type: | Small molecule |
| Compound Name: | PREDNISONE |
| Synonyms: | 3EN3HG4WSW|CORTAN|CORTANCYL|DECORTIN|DECORTISYL|DEHYDROCORTISONE|Delta-dome|Deltasone|FERNISONE|LIQUID PRED|LODOTRA|METACORTANDRACIN|Meticorten|NSC-10023|Orasone|PARACORT|PREDNICEN-M|PREDNISONE|PREDNISONE ANHYDROUS|PREDNISONE INTENSOL|PREDNISONE TABLETS|Prednisone|RAYOS|SERVISONE|SUPERCORTIL|Sterapred |
| Molecular Formula: | C21H26O5 |
| SMILES: | C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |