Bioactive Compound Details
| Compound ID: | B144996 |
| Source ID: | CHEMBL643 |
| Source Type: | Small molecule |
| Compound Name: | PROMETHAZINE |
| Synonyms: | DIMAPP|DIPHERGAN|FARGAN|NSC-30321|PROAZAMINE|PROCIT|PROMETAZIN|PROMETHAZINE|PROTAZINE|PROTHAZIN|Phenergan|Promethacon|Promethazine|Promethegan|RP-3277|Remsed|VALLERGINE|Zipan-25|Zipan-50 |
| Molecular Formula: | C17H20N2S |
| SMILES: | CC(CN1c2ccccc2Sc2ccccc21)N(C)C |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |