Bioactive Compound Details
| Compound ID: | B145123 |
| Source ID: | CHEMBL6966 |
| Source Type: | Small molecule |
| Compound Name: | VERAPAMIL |
| Synonyms: | CP-16,533-1|CP-16533-1|CP-165331|Calan|Covera-HS|D-365|IPROVERATRIL|Isoptin|NSC-272306NA|Tarka|VERAPAMIL|VERAPAMIL SLOW RELEASE|Verapamil|Verelan |
| Molecular Formula: | C27H38N2O4 |
| SMILES: | COc1ccc(CCN(C)CCCC(C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T06 | Glucagon-like peptide 1 receptor | GLP1R | agonist | GPCR | P43220 | GLP1R_HUMAN | Details |