Bioactive Compound Details
| Compound ID: | B145164 |
| Source ID: | CHEMBL70927 |
| Source Type: | Small molecule |
| Compound Name: | DEFERIPRONE |
| Synonyms: | APO-066|APO-66|CP-20|CP20|DEFERIPRON|DEFERIPRONE|DN-180-01-AF|DN-18001AF|FERRIPROX|L-1|L1|NSC-758880|PL-1|PL1 |
| Molecular Formula: | C7H9NO2 |
| SMILES: | Cc1c(O)c(=O)ccn1C |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |