Bioactive Compound Details
| Compound ID: | B145191 |
| Source ID: | CHEMBL716 |
| Source Type: | Small molecule |
| Compound Name: | QUETIAPINE |
| Synonyms: | ATROLAK XL|BIQUELLE XL|BRANCICO XL|EBESQUE XL|MINTRELEQ XL|NORSIC|NSC-758918|PSYQUET XL|QUETIAPINE|QUETIAPINE EXTENDED RELEASE|Quetiapine|SEOTIAPIM XL|SEROQUEL|SEROQUEL XL|SONDATE XL|TENPROLIDE XL|ZALURON XL |
| Molecular Formula: | C21H25N3O2S |
| SMILES: | OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |