Bioactive Compound Details
| Compound ID: | B145208 |
| Source ID: | CHEMBL723 |
| Source Type: | Small molecule |
| Compound Name: | CARVEDILOL |
| Synonyms: | BM 14.190|BM-14-190|BM-14.190|BM-14190|C07AG02|CARVEDILOL|COREG|CORONIS|Coreg CR|DILATREND|DIMITONE|DQ-2466|EUCARDIC|EUCARDIC 12.5|EUCARDIC 25|EUCARDIC 3.125|EUCARDIC 6.25|KORVASAN|KREDEX|NSC-758694|SKF-105517|TALLITON |
| Molecular Formula: | C24H26N2O4 |
| SMILES: | COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T09 | Toll-like receptor 4 | TLR4 | antagonist | Membrane receptor | O00206 | TLR4_HUMAN | Details |