Bioactive Compound Details
| Compound ID: | B145240 |
| Source ID: | CHEMBL741 |
| Source Type: | Small molecule |
| Compound Name: | LAMOTRIGINE |
| Synonyms: | BW 430C|BW-430C|LAMICTAL CD|LAMICTAL ODT|LAMICTAL XR|LAMOTRIGINE|Lamictal|NSC-759171 |
| Molecular Formula: | C9H7Cl2N5 |
| SMILES: | Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |