Bioactive Compound Details
| Compound ID: | B145486 |
| Source ID: | CHEMBL838 |
| Source Type: | Small molecule |
| Compound Name: | BENAZEPRIL |
| Synonyms: | BENAZEPRIL|BENAZEPRIL SANDOZ|BRIEM|Benazepril|C09AA07|CGS-14824A|CIBACEN WS|CIBACENE|FORTEEKOR|Lotensin|Lotrel |
| Molecular Formula: | C24H28N2O5 |
| SMILES: | CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCc2ccccc2N(CC(=O)O)C1=O |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |