Bioactive Compound Details
| Compound ID: | B145538 |
| Source ID: | CHEMBL865 |
| Source Type: | Small molecule |
| Compound Name: | VALDECOXIB |
| Synonyms: | Bextra|NSC-759846|SC-65872|VALDECOXIB|VALDYN |
| Molecular Formula: | C16H14N2O3S |
| SMILES: | Cc1onc(-c2ccccc2)c1-c1ccc(S(N)(=O)=O)cc1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |