Bioactive Compound Details
| Compound ID: | B145615 |
| Source ID: | CHEMBL894 |
| Source Type: | Small molecule |
| Compound Name: | BUPROPION |
| Synonyms: | AMFEBUTAMONE|BUPROPION|BUPROPION EXTENDED RELEASE|BUPROPION SLOW RELEASE|Bupropion|NSC-758686 |
| Molecular Formula: | C13H18ClNO |
| SMILES: | CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |