Bioactive Compound Details
| Compound ID: | B145656 |
| Source ID: | CHEMBL90555 |
| Source Type: | Small molecule |
| Compound Name: | VINCRISTINE |
| Synonyms: | 22-OXOVINCALEUKOBLASTINE|LEUCRISTINE|LEUROCRISTINE|ONCOTCS|TECNOCRIS|VINCALEUKOBLASTINE, 22-OXO-|VINCRISTIN|VINCRISTINE|VINKRISTIN|Vincristine |
| Molecular Formula: | C46H56N4O10 |
| SMILES: | CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C=O)[C@H]3[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)C2)C1 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |