Bioactive Compound Details
| Compound ID: | B145869 |
| Source ID: | CHEMBL989 |
| Source Type: | Small molecule |
| Compound Name: | FLUOCINOLONE ACETONIDE |
| Synonyms: | CAPEX|DERMOTIC|Derma-Smoothe/FS|FLUCINOLONE ACETONIDE|FLUOCINOLIDE (ACETATE)|FLUOCINOLONE|FLUOCINOLONE ACETONIDE|FS Shampoo|Fluocet|Fluonid|Fluotrex|ILUVIEN|NSC-92339|OTO-SYNALAR|Retisert|SYNALAR FTE|SYNALAR-C|SYNALAR-HP|SYNALAR-N|SYNANDONE|Synalar|YUTIQ |
| Molecular Formula: | C24H30F2O6 |
| SMILES: | CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |