Bioactive Compound Details
| Compound ID: | B145872 |
| Source ID: | CHEMBL991 |
| Source Type: | Small molecule |
| Compound Name: | STAVUDINE |
| Synonyms: | BMY-27857|D-4T|D4T|NSC-163661|NSC-759897|SANILVUDINE|STAVUDINE|STAVUDINE (D4T)|STAVUDINE (DT4)|STAVUDINUM|ZERIT XR|Zerit|d4T |
| Molecular Formula: | C10H12N2O4 |
| SMILES: | Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |