Bioactive Compound Details

Compound ID: B001491
Source ID: CHEMBL1173655
Source Type: Small molecule
Compound Name: AFATINIB
Synonyms: AFATINIB|BIBW 2992|BIBW-2992|BIBW2992|GILOTRIF|GIOTRIF|NSC-750691|TOMTOVOK|TOVOK
Molecular Formula: C24H25ClFN5O3
SMILES: CN(C)C/C=C/C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1
Molecular Species: BASE

Target ID Target Name GENE Action Class UniProtKB ID Entry Name
T14 Mitogen-activated protein kinase kinase kinase 5 MAP3K5 inhibitor Enzyme Q99683 M3K5_HUMAN Details
T42 Serine/threonine-protein kinase 17B STK17B inhibitor Kinase O94768 ST17B_HUMAN Details