Bioactive Compound Details
| Compound ID: | B001503 |
| Source ID: | CHEMBL1177 |
| Source Type: | Small molecule |
| Compound Name: | PEMOLINE |
| Synonyms: | AZOKSODON|AZOXODON|AZOXODONE|CENTRAMIN|Cylert|DANTROMIN|DELTAMIN|DELTAMINE|FENOXAZOL|HYTON|HYTON ASA|KETHAMED|LA-956|NITAN|NSC-169499|NSC-25159|OKODON|PEMOLIN|PEMOLINE|PHENIMINOOXAZOLIDINONE|PHENOXAZOLE|PHENYLISOHYDANTOIN|PHENYLPSEUDOHYDANTOIN|PIOXOL|PONDEX|RONYL|SIGMADYN|SISTRA|STIMUL|STIMULOL|TRADON|TRADONE|VOLITAL|YH-1 |
| Molecular Formula: | C9H8N2O2 |
| SMILES: | NC1=NC(=O)C(c2ccccc2)O1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |