Bioactive Compound Details
| Compound ID: | B001653 |
| Source ID: | CHEMBL1200545 |
| Source Type: | Small molecule |
| Compound Name: | DIFLORASONE DIACETATE |
| Synonyms: | DIFLORASONE|DIFLORASONE DIACETATE|FLORONE E|Florone|MURODE|PSORCON E|Psorcon|U-34,865|U-34865 |
| Molecular Formula: | C26H32F2O7 |
| SMILES: | CC(=O)OCC(=O)[C@@]1(OC(C)=O)[C@@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |