Bioactive Compound Details
| Compound ID: | B001730 |
| Source ID: | CHEMBL1201139 |
| Source Type: | Small molecule |
| Compound Name: | MEGESTROL ACETATE |
| Synonyms: | 5071|BDH 1298|BDH-1298|CHRONOPIL|MEGACE ES|MEGESTEROL ACETATE|MEGESTROL|MEGESTROL 17.ALPHA.-ACETATE|MEGESTROL ACETATE|Megace|NSC-71423|Ovaban|SC 10363|SC-10363 |
| Molecular Formula: | C24H32O4 |
| SMILES: | CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |