Bioactive Compound Details

Compound ID: B002114
Source ID: CHEMBL1230609
Source Type: Small molecule
Compound Name: FORETINIB
Synonyms: EXEL-2880|FORETINIB|Foretinib|GSK-089|GSK-1363089|GSK-1363089G|GSK089|GSK1363089|GSK1363089G|XL-880|XL880
Molecular Formula: C34H34F2N4O6
SMILES: COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1
Molecular Species: NEUTRAL

Target ID Target Name GENE Action Class UniProtKB ID Entry Name
T14 Mitogen-activated protein kinase kinase kinase 5 MAP3K5 inhibitor Enzyme Q99683 M3K5_HUMAN Details
T42 Serine/threonine-protein kinase 17B STK17B inhibitor Kinase O94768 ST17B_HUMAN Details