Bioactive Compound Details
| Compound ID: | B021247 |
| Source ID: | CHEMBL137 |
| Source Type: | Small molecule |
| Compound Name: | METRONIDAZOLE |
| Synonyms: | ACEA|ANABACT|BAY-5360|BAYER 5360|BAYER-5360|DEFLAMON|DRAZIFON|ELYZOL|FLAGYL COMPAK|FLAGYL ER|FLAGYL-400|FLAGYL-S|Flagyl|Flagyl 375|Flagyl i.v. rtu in plastic container|GINEFLAVIR|METRO I.V.|METROCREAM|METROGEL-VAGINAL|METROLOTION|METROLYL|METROMIDOL|METRONIDAZOLE|METROSA|METROTOP|Metric 21|Metrogel|NEUTRATOP|NORZOL|NSC-50364|NSC-69587|NUVESSA|Noritate|ORVAGIL|PROTOSTAT|ROSICED|ROZEX|RP 8823|RP-8823|SATRIC|VAGINYL|Vandazole|ZADSTAT|ZIDOVAL|ZYOMET |
| Molecular Formula: | C6H9N3O3 |
| SMILES: | Cc1ncc([N+](=O)[O-])n1CCO |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |