Bioactive Compound Details
| Compound ID: | B021248 |
| Source ID: | CHEMBL1370 |
| Source Type: | Small molecule |
| Compound Name: | BUDESONIDE |
| Synonyms: | AIRCORT|BUDEFLAM AQUANASE|BUDELIN NOVOLIZER|BUDENOFALK|BUDESONIDE|CORTIMENT|DUORESP SPIROMAX|ENTOCORT|ENTOCORT CR|ENTOCORT EC|MAP-0010|MAP0010|NSC-757788|ORTIKOS|PREFERID|PULMAXAN|PULMICORT FLEXHALER|PULMICORT L.S.|PULMICORT RESPULES|Pulmicort|R01AD05|RHINOCORT ALLERGY|RHINOCORT AQUA|RHINOCORT AQUA 64|Rhinocort|S-1320|SYMBICORT|UCERIS |
| Molecular Formula: | C25H34O6 |
| SMILES: | CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T06 | Glucagon-like peptide 1 receptor | GLP1R | agonist | GPCR | P43220 | GLP1R_HUMAN | Details |