Bioactive Compound Details
| Compound ID: | B002172 |
| Source ID: | CHEMBL1236282 |
| Source Type: | Small molecule |
| Compound Name: | THIAMPHENICOL |
| Synonyms: | ARMAI|Dextrosulphenidol|NSC-522822|THIAMPHENICOL|THIAMPHENICOL AMINOACETATE HYDROCHLORIDE|Thiocymetin|Thiophenicol|WIN 5063-2|WIN-5063-2 |
| Molecular Formula: | C12H15Cl2NO5S |
| SMILES: | CS(=O)(=O)c1ccc([C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl)cc1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |