Bioactive Compound Details
| Compound ID: | B000025 |
| Source ID: | CHEMBL101 |
| Source Type: | Small molecule |
| Compound Name: | PHENYLBUTAZONE |
| Synonyms: | AMBENE|ARTRIZIN|Antadol|Azolid|BIZOLIN|BUTACOTE|BUTADION|BUTADIONA|BUTAPIRAZOL|BUTATRON|BUTOZ|BUZON|Butaject|Butazolidin|DIPHEBUZOL|DIPHENYLBUTAZONE|ECOBUTAZONE|EQUIPALAZONE|EXRHEUDON N|Elmedal|Equiphar|FENIBUTAZONA|FENIBUTOL|FENYLBUTAZON|FLEXAZONE|G-13871|INTRABUTAZONE|INTRAZONE|MEPHA-BUTAZON|NSC-25134|PHEBUZINE|PHENYLBUTAZONE|PHENYZENE|Phenylbutazone|Pro-Bute|R-3-ZON|ROBIZONE-V|SHIGRODIN|TEVCODYNE|UZONE|ZOLAPHEN |
| Molecular Formula: | C19H20N2O2 |
| SMILES: | CCCCC1C(=O)N(c2ccccc2)N(c2ccccc2)C1=O |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |