Bioactive Compound Details
| Compound ID: | B030509 |
| Source ID: | CHEMBL1405 |
| Source Type: | Small molecule |
| Compound Name: | ESTRONE |
| Synonyms: | 1,3,5-ESTRATRIEN-3-OL-17-ONE|ESTRADIOL METABOLITE E1|ESTROGENIC SUBSTANCE|ESTRONE|Estrone|FOLLICULAR HORMONE|FOLLICULAR-HORMONE|FOLLICULIN|FOLLICULINUM|KETOHYDROXYESTRIN|NATURAL ESTROGENIC SUBSTANCE-ESTRONE|NSC-9699|OESTRONE|Oestrone|THELYKININ|TOKOKIN|Theelin|WAY 164397 |
| Molecular Formula: | C18H22O2 |
| SMILES: | C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |