Bioactive Compound Details
| Compound ID: | B000379 |
| Source ID: | CHEMBL108 |
| Source Type: | Small molecule |
| Compound Name: | CARBAMAZEPINE |
| Synonyms: | ARBIL MR|BISTON|CARBAGEN SR|CARBAMAZEPINE|CARBAMAZEPINE ANHYDROUS|CARBAMAZEPINE EXTENDED RELEASE|CARBAMAZEPINUM|CARNEXIV|Carbatrol|EPIMAZ|EPIMAZ RET|Epitol|Equetro|FINLEPSIN|G-32883|GEIGY 32883|KARBAMAZEPIN|KARBELEX|NEUROTOL|NEUROTOP|NSC-169864|SIRTAL|SIRTAL RET|STAZEPINE|TEGRETAL|TEGRETOL CHEWTAB|TEGRETOL PROLONGED RELEASE|TEGRETOL-XR|TELESMIN|TERIL RET|TIMONIL|TIMONIL 200 RET|TIMONIL 400 RET|Tegretol|Tegretol XR|Teril |
| Molecular Formula: | C15H12N2O |
| SMILES: | NC(=O)N1c2ccccc2C=Cc2ccccc21 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |