Bioactive Compound Details
| Compound ID: | B046874 |
| Source ID: | CHEMBL1467 |
| Source Type: | Small molecule |
| Compound Name: | ALLOPURINOL |
| Synonyms: | ALLOPURINOL|ALLOPURINOLUM|ALORAL|ALULINE 100|ALULINE 300|BW 56-158|BW-56-158|CAPLENAL|COSURIC|HAMARIN 100|HAMARIN 300|LEDOPUR|LOPURIN|NSC-101655|NSC-1390|SUSPENDOL|TAKANARUMIN|URICTO|XANTHOMAX-100|XANTHOMAX-300|ZYLORIC|ZYLORIC-300|Zyloprim |
| Molecular Formula: | C5H4N4O |
| SMILES: | O=c1ncnc2[nH][nH]cc1-2 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |