Bioactive Compound Details
| Compound ID: | B053346 |
| Source ID: | CHEMBL1491 |
| Source Type: | Small molecule |
| Compound Name: | AMLODIPINE |
| Synonyms: | AMLODIPINE|ASTUDAL 5|CKD-330 COMPONENT AMLODIPINE|HGP-0904|HGP0904|ISTIN|NORVAS|NORVASC |
| Molecular Formula: | C20H25ClN2O5 |
| SMILES: | CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |