Bioactive Compound Details
| Compound ID: | B005561 |
| Source ID: | CHEMBL131 |
| Source Type: | Small molecule |
| Compound Name: | PREDNISOLONE |
| Synonyms: | CORTALONE|DEKOTIL|DELTACORTRIL|DELTALONE|DILACORT|Delta-cortef|Desowen|FERNISOLONE-P|Hydeltra|Hydeltra-Tba|Meti-derm|Meticortelone|NSC-9120|NSC-9900|Neo-Delta-Cortef|PEVANTI|PRECORTISYL|PRECORTISYL FTE|PREDNISOLONE|PRELONE|Poly-Pred|Pred-G|Prednisolone|SCHERIPROCT|Servisone|Sterane|Tridesilon|Verdeso |
| Molecular Formula: | C21H28O5 |
| SMILES: | C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |