Bioactive Compound Details
| Compound ID: | B056824 |
| Source ID: | CHEMBL1504 |
| Source Type: | Small molecule |
| Compound Name: | TRIAMCINOLONE ACETONIDE |
| Synonyms: | ADCORTYL|ADCORTYL IN ORABASE|ALLERNAZE|ARISTOCORT A|ARISTOGEL|AUDICORT|AUREOCORT|Aristocort|Azmacort|FLUTEX|FX-006|FX006|GPPE EAR DPS CAP|GPPE EAR OINT|KENACORT|KENALOG IN ORABASE|KENALOG-10|KENALOG-40|KENALOG-80|KENALOG-H|Kenacourt|Kenalog|NASACORT ALLERGY 24 HOUR|NASACORT AQ|NASACORT HFA|NSC-21916|NYSTADERMAL|Nasacort|Oracort|Oralone|PEVARYL T.C.|REMIDERM|REMOTIC|SILDERM|TRI-ADCORTYL|TRIACORT|TRIAMCINOLONE ACETONIDE|TRIAMCINOLONE ACETONIDE IN ABSORBASE|TRIATEX|TRIESENCE|TRIVARIS|TRYMEX|Tri-nasal|Triacet|Triamcinolone Acetonide|Triderm|Vetalog|ZILRETTA |
| Molecular Formula: | C24H31FO6 |
| SMILES: | CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |