Bioactive Compound Details
| Compound ID: | B082365 |
| Source ID: | CHEMBL1601669 |
| Source Type: | Small molecule |
| Compound Name: | ALFACALCIDOL |
| Synonyms: | .ALPHA.-CALCIDOL|1-ALPHA-VITAMIN D|1-HYDROXYCHOLECALCIFEROL|1-HYDROXYVITAMIN D3|1.ALPHA-HYDROXYCHOLECALCIFEROL|1.ALPHA.(OH)D3|1.ALPHA.-HYDROXYCHOLECALCIFEROL|1.ALPHA.-HYDROXYVITAMIN D3|ALFA D|ALFACALCIDOL|ALFAROL|ALPHA D3|ALPHACALCIDOL|ALPHAROL|ALSIODOL|BONDIOL|EINSALPHA|ETALPHA|ONE-ALPHA|OXYDEVIT|TEVABONE|UN ALFA|UN ALPHA |
| Molecular Formula: | C27H44O2 |
| SMILES: | C=C1/C(=C\C=C2/CCC[C@@]3(C)[C@H]2CC[C@@H]3[C@H](C)CCCC(C)C)C[C@@H](O)C[C@@H]1O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |