Bioactive Compound Details
| Compound ID: | B085455 |
| Source ID: | CHEMBL1619 |
| Source Type: | Small molecule |
| Compound Name: | CLADRIBINE |
| Synonyms: | 2-CDA|CLADARIBINE|CLADRIBINE|LEUSTAT|LITAK|Leustatin|MAVENCLAD|NSC-05014|NSC-105014|NSC-105014-F|RWJ 26251|RWJ-26251 |
| Molecular Formula: | C10H12ClN5O3 |
| SMILES: | Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T06 | Glucagon-like peptide 1 receptor | GLP1R | agonist | GPCR | P43220 | GLP1R_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |