Bioactive Compound Details
| Compound ID: | B085596 |
| Source ID: | CHEMBL163 |
| Source Type: | Small molecule |
| Compound Name: | RITONAVIR |
| Synonyms: | A-84538|ABBOTT-84538|ABT-538|EMPETUS|NSC-693184|Norvir|RITOMUNE|RITONAVIR|RITONAVIR RELATED COMPOUNDS MIXTURE|RITONAVIRUM|RITOVIR|VIEKIRAX|VIRITON |
| Molecular Formula: | C37H48N6O5S2 |
| SMILES: | CC(C)c1nc(CN(C)C(=O)N[C@H](C(=O)N[C@@H](Cc2ccccc2)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |