Bioactive Compound Details
| Compound ID: | B092669 |
| Source ID: | CHEMBL1726 |
| Source Type: | Small molecule |
| Compound Name: | NISOLDIPINE |
| Synonyms: | BAY K 5552|BAY-K-5552|BAYMYCARD|GEOMATRIX 16E|NISOLDIPIN|NISOLDIPINE|NISOLDIPINE (STN)|NSC-759106|SYSCOR MR 10|SYSCOR MR 20|SYSCOR MR 30|Sular |
| Molecular Formula: | C20H24N2O6 |
| SMILES: | COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)C)C1c1ccccc1[N+](=O)[O-] |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |