Bioactive Compound Details
| Compound ID: | B095250 |
| Source ID: | CHEMBL1741 |
| Source Type: | Small molecule |
| Compound Name: | CLARITHROMYCIN |
| Synonyms: | 6-O-METHYLERYTHROMYCIN|A-56268|ABBOTT-56268|BIAXIN XL|Biaxin|Biaxin XL Pac|CLARIE XL|CLARITHROMYCIN|CLARITHROMYCIN IDENTITY|CLAROSIP|CYLLIND|Clarithromycin extended release|ERYTHROMYCIN, 6-O-METHYL-|FEBZIN XL|KLACID|KLARICID|KLARICID 500|KLARICID ADULT|KLARICID I.V.|KLARICID PAED|KLARICID XL|MACLADIN|MAVID|MYCIFOR XL|NSC-758704|Prevpac|TE-031|VECLAM|XETININ XL|ZECLAR |
| Molecular Formula: | C38H69NO13 |
| SMILES: | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |