Bioactive Compound Details

Compound ID: B095972
Source ID: CHEMBL180022
Source Type: Small molecule
Compound Name: NERATINIB
Synonyms: CDP-820|HKI-272|NERATINIB|Neratinib|WAY-179272
Molecular Formula: C30H29ClN6O3
SMILES: CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)/C=C/CN(C)C
Molecular Species: BASE

Target ID Target Name GENE Action Class UniProtKB ID Entry Name
T14 Mitogen-activated protein kinase kinase kinase 5 MAP3K5 inhibitor Enzyme Q99683 M3K5_HUMAN Details
T42 Serine/threonine-protein kinase 17B STK17B inhibitor Kinase O94768 ST17B_HUMAN Details