Bioactive Compound Details
| Compound ID: | B096129 |
| Source ID: | CHEMBL181 |
| Source Type: | Small molecule |
| Compound Name: | DIAZOXIDE |
| Synonyms: | DIAZOXIDE|DIAZOXIDUM|EUDEMINE|EUDEMINE INJECTION|Eudimine|HYPERSTAT|HYPERTONALUM|Mutabase|NSC-64198|NSC-76130|Proglycem|SCH 6783|SCH-6783|SRG 95213|SRG-95213 |
| Molecular Formula: | C8H7ClN2O2S |
| SMILES: | CC1=NS(=O)(=O)c2cc(Cl)ccc2N1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |