Investigational Drug Details
| Drug ID: | D317 |
| Drug Name: | Saffron |
| Synonyms: | Crocus sativus |
| Type: | Herbal medicine |
| DrugBank ID: | -- |
| DrugBank Description: | -- |
| PubChem ID: | 5281233 |
| CasNo: | 89382-88-7 |
| Repositioning for NAFLD: | No |
| SMILES: | -- |
| InChiKey: | -- |
| Molecular Weight: | -- |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Phase 2 on-going (IRCT201610269472N11) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0562 | IRCT201610269472N11 | Phase 2 | Recruiting | No Results Available | 22/11/2016 | 22 February 2018 | Details |
| L0816 | IRCT201705309472N13 | Phase 2/Phase 3 | Recruiting | No Results Available | 26/07/2017 | 22 February 2018 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A01161 | 34848360 | J Ethnopharmacol | Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model. | Details |
| A02970 | 34179049 | Front Med (Lausanne) | Exploring the Protective Effects and Mechanism of Crocetin From Saffron Against NAFLD by Network Pharmacology and Experimental Validation. | Details |
| A06639 | 32798261 | Phytother Res | The effect of saffron supplementation on some inflammatory and oxidative markers, leptin, adiponectin, and body composition in patients with nonalcoholic fatty liver disease: A double-blind randomized clinical trial. | Details |
| A16162 | 28529733 | Biomed Rep | Metabolic effects of Crocus sativus and protective action against non-alcoholic fatty liver disease in diabetic rats. | Details |
| A17473 | 27770798 | BMC Complement Altern Med | Protective effects of saffron extract and crocin supplementation on fatty liver tissue of high-fat diet-induced obese rats. | Details |