| Trial ID: | L0816 |
| Source ID: | IRCT201705309472N13
|
| Associated Drug: |
Saffron
|
| Title: |
Effect of saffron powder on serum concentration of hs-CRP, TNF-a, MDA, TAC, adiponectin and leptin in patients with non-alcoholic fatty live disease
|
| Acronym: |
--
|
| Status: |
Recruiting
|
| Study Results: |
No Results Available
|
| Results: |
--
|
| Conditions: |
non alcoholic fatty liver disease. <br>Fatty (change of) liver, not elsewhere classified;Fatty (change of) liver, not elsewhere classified
|
| Interventions: |
Intervention 1: Saffron powder group: One day, one tablet will contain 100 mg of saffron for 3 months (12 weeks). Intervention 2: Placebo group: For a period of 3 months (12 weeks), one tablet will contain 100 mg dextrose malto.;Treatment - Drugs;Treatmen
|
| Outcome Measures: |
Hs-crp. Timepoint: Before intervention and 3 months after intervention. Method of measurement: ELISA kit in ng / ml.;ALT. Timepoint: Before intervention and 3 months after intervention. Method of measurement: Enzymatic photometric.;AST. Timepoint: Before intervention and 3 months after intervention. Method of measurement: Enzymatic photometric.Waist to hip ratio (WHR). Timepoint: Before the intervention and three months after the intervention. Method of measurement: calculation.;TNF-a. Timepoint: Before the intervention and three months after the intervention. Method of measurement: ELISA kit in pg / ml.;TAC. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Using the kits and colorimetric method in umol / L.;Adiponectin. Timepoint: Before the intervention and three months after the intervention. Method of measurement: ELISA kit in ng / ml.;Leptin. Timepoint: Before the intervention and three months after the intervention. Method of measurement: ELISA kit in ng / ml.;Malondialdehyde (MDA). Timepoint: Before the intervention and three months after the intervention. Method of measurement: Colorimetric method ng / ml.;Weight. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Digital scale in kilograms.;Body mass index (BMI). Timepoint: Before the intervention and three months after the intervention. Method of measurement: Calculation / in kg / m2.;Waist. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Meter in cm.;Hip circumference. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Meter in cm.;Body fat percentage. Timepoint: Before the intervention and three months after the intervention. Method of measurement: ebody device BIA method.
|
| Sponsor/Collaborators: |
Deputy of Research of Iran University of Medical Sciences
|
| Gender: |
All
|
| Age: |
18 years65 years
|
| Phases: |
Phase 2/Phase 3
|
| Enrollment: |
76
|
| Study Type: |
interventional
|
| Study Designs: |
Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive.
|
| Start Date: |
26/07/2017
|
| Completion Date: |
--
|
| Results First Posted: |
--
|
| Last Update Posted: |
22 February 2018
|
| Locations: |
Iran (Islamic Republic of)
|
| URL: |
http://en.irct.ir/trial/10060
|
