Investigational Drug Details
| Drug ID: | D076 |
| Drug Name: | Chromium picolinate |
| Synonyms: | Chromium(III) picolinate |
| Type: | Chemical drug |
| DrugBank ID: | DB11255 |
| DrugBank Description: | Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss. Chromium ions are shown to regulate insulin by promoting glucose utilization and increasing the sensitivity of the insulin receptor . |
| PubChem ID: | 151932 |
| CasNo: | 14639-25-9 |
| Repositioning for NAFLD: | Yes |
| SMILES: | [Cr+3].[O-]C(=O)c1ncccc1.[O-]C(=O)c1ncccc1.[O-]C(=O)c1ncccc1 |
| Structure: |
|
| InChiKey: | CBDQOLKNTOMMTL-UHFFFAOYSA-K |
| Molecular Weight: | 418.305 |
| DrugBank Targets: | -- |
| DrugBank MoA: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank Indication: | -- |
| Targets: | -- |
| Therapeutic Category: | -- |
| Clinical Trial Progress: | Clinical trial on-going (IRCT20100123003140N15) |
| Latest Progress: | Under clinical trials |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0512 | IRCT20100123003140N15 | Phase 2/Phase 3 | Recruiting | No Results Available | 14/01/2018 | 22 February 2018 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Article ID | PMID | Source | Title | |
|---|---|---|---|---|
| A05997 | 33045675 | J Trace Elem Med Biol | A pilot study of the effects of chromium picolinate supplementation on serum fetuin-A, metabolic and inflammatory factors in patients with nonalcoholic fatty liver disease: A double-blind, placebo-controlled trial. | Details |
| A06622 | 32804855 | Eur J Gastroenterol Hepatol | Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial. | Details |
| A37262 | 16117721 | Dis Manag | Use of chromium picolinate and biotin in the management of type 2 diabetes: an economic analysis. | Details |