Investigational Drugs

Investigational drugs for NAFLD are derived from global clinical trials with the latest progress, and detailed drug properties are extracted from DrugBank and PubChem. For each drug, related therapeutic strategies, targets, and clinical trials in NAFLDkb are presented with knowledge graphs.

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     Hypertension
16 records.
Drug ID Drug Name Type DrugBank ID Targets Category Latest Progress
D028 Belapectin Chemical drug DB15125 Gelactin-3 inhibitor; LGALS3 inhibitor Anti-fibrosis Failed in clinical trials Details
D033 Bezafibrate Chemical drug DB01393 PPARA agonist; PPARD agonist; PPARG agonist; NR1I2 partial agonist Improve insulin resistance; Anti-inflammatory Under clinical trials Details
D084 Coenzyme Q10 Chemical drug DB09270 -- -- Under clinical trials Details
D209 Losartan Chemical drug DB00678 AGTR1 antagonist&binder Anti-fibrosis Under clinical trials Details
D232 Moxonidine Chemical drug DB09242 NISCH agonist -- Under clinical trials Details
D248 Obeticholic Acid Chemical drug DB05990 NR1H4 activator; NR1H4 agonist; FXR agonist Enhance lipid metabolism Approval rejected Details
D267 Perindopril Chemical drug DB00790 ACE inhibitor Antihypertensive drug Under clinical trials Details
D271 Phentermine Chemical drug DB00191 MAOB antagonist; MAOA antagonist; SLC6A2 inhibitor; SLC6A3 inhibitor; SLC6A4 inhibitor; SLC6A2 stimulator; SLC6A3 stimulator Anorexic; CNS stimulant Under clinical trials Details
D344 Spironolactone Chemical drug DB00421 AR antagonist; PGR agonist; NR1I2 Diuretic drug Under clinical trials Details
D360 Telmisartan Chemical drug DB00966 PPARG partial agonist Improve insulin resistance Under clinical trials Details
D385 Vitamin B6 Supplement DB00165 PDXK ligand -- Under clinical trials Details
D476 Estradiol Chemical drug DB00783 -- -- Under clinical trials Details
D480 Guanabenz Chemical drug DB00629 -- -- Under clinical trials Details
D533 Lisinopril Chemical drug DB00722 ACE inhibitor -- Under clinical trials Details
D538 Mazindol Chemical drug DB00579 -- -- Under clinical trials Details
D541 Olmesartan Chemical drug DB00275 -- -- Under clinical trials Details