| Trial ID: | L0013 |
| Source ID: | NCT00262964
|
| Associated Drug: |
Niacin
|
| Title: |
Obesity and Nonalcoholic Fatty Liver Disease
|
| Acronym: |
--
|
| Status: |
Completed
|
| Study Results: |
Has Results
|
| Results: |
https://ClinicalTrials.gov/show/NCT00262964/results
|
| Conditions: |
Non-alcoholic Fatty Liver Disease
|
| Interventions: |
Drug: Niacin|Drug: fenofibrate|Drug: placebo
|
| Outcome Measures: |
Hepatic Insulin Sensitivity Index (HISI)|Percent Increase in Skeletal Muscle Insulin Sensitivity During Insulin Infusion.|Adipose Tissue Insulin Sensitivity|Hepatic Fat Content for Fenofibrate and Niacin Groups|Adipose Tissue Insulin Sensitivity in Fenofibrate and Niacin Groups|Change From Baseline in Skeletal Muscle Insulin Sensitivity|Change From Baseline in Hepatic Insulin Sensitivity Index|Very Low Density Lipoprotein - Triglyceride Production Rate|Change From Baseline in Very Low Density Lipoprotein Apolipoprotein B Production Rate|Change From Baseline in VLDL-Tg Clearance Rate|Change From Baseline in VLDL-Tg Production Rate|Change From Baseline in Very Low-density Lipoprotein Triglyceride Concentration
|
| Sponsor/Collaborators: |
Washington University School of Medicine|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
|
| Gender: |
All
|
| Age: |
18 Years to 45 Years ?? (Adult)
|
| Phases: |
Not applicable
|
| Enrollment: |
51
|
| Study Type: |
Interventional
|
| Study Designs: |
Allocation: Randomized|Intervention Model: Factorial Assignment|Masking: Single (Participant)|Primary Purpose: Treatment
|
| Start Date: |
October 2004
|
| Completion Date: |
December 2008
|
| Results First Posted: |
June 28, 2010
|
| Last Update Posted: |
July 11, 2018
|
| Locations: |
Washington University School of Medicine, Saint Louis, Missouri, United States
|
| URL: |
https://ClinicalTrials.gov/show/NCT00262964
|
