| Trial ID: | L0527 |
| Source ID: | NCT03222206
|
| Associated Drug: |
Salsalate
|
| Title: |
The Comparison of Effect Between Salsalate and Placebo in Osteoarthritis With Nonalcoholic Fatty Liver Disease: Investigator Initiated Randomized Placebo-controlled Double-blind, Pilot Study
|
| Acronym: |
--
|
| Status: |
Not recruiting
|
| Study Results: |
No Results Available
|
| Results: |
--
|
| Conditions: |
Non Alcoholic Fatty Liver;Osteo Arthritis
|
| Interventions: |
Drug: Salsalate;Other: Placebo
|
| Outcome Measures: |
Change of controlled attenuation parameter;Change of hepatokine as Fetuin-A;Change of pulse wave velocity;Change of adipokine as AdiponectinChange of controlled attenuation parameter;Change of hepatokine as Fetuin-A;Change of pulse wave velocity;Change of adipokine as Adiponectin;Numerical value change of fatty liver index;Numerical value change of hepatic fibrosis as Nonalcoholic Fatty Liver Disease(NAFLD) fibrosis score;Change of saccharometabolic factors as Homeostasis Model Assessment(HOMA)-Insulin Resistance(IR), Homeostasis Model Assessment(HOMA)-B, Fasting glucose, Insulin, C-peptide, HbA1c, Glycated albumin;Change of lipid metabolic factors as Cholesterol, Triglyceride, LDL-cholesterol HDL-cholesterol and liver function test as Aspartate Transaminase(AST) and Alanine Transaminase(ALT);Change of inflammatory factors as C Reactive Protein(CRP), Tumor Necrosis Factor(TNF)-a;Change of liver fibrosis factors as hyaluronic acid;Change of symptom of osteoarthritis as visual analog score for pain;Change of function of osteoarthritis as WOMAC (The Western Ontario and McMaster Universities Osteoarthritis Index);Stability comparison like side effect
|
| Sponsor/Collaborators: |
Korea University Guro Hospital
|
| Gender: |
All
|
| Age: |
19 Yearsnan
|
| Phases: |
Phase 4
|
| Enrollment: |
34
|
| Study Type: |
Interventional
|
| Study Designs: |
Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: Double (Participant, Investigator).
|
| Start Date: |
08/07/2017
|
| Completion Date: |
--
|
| Results First Posted: |
--
|
| Last Update Posted: |
12 December 2020
|
| Locations: |
Korea, Republic of
|
| URL: |
https://clinicaltrials.gov/show/NCT03222206
|
