Clinical Trial Details
| Trial ID: | L0055 |
| Source ID: | NCT04142749 |
| Associated Drug: | Oltipraz |
| Title: | Oltipraz for Liver Fat Reduction in Patients With Non-alcoholic Fatty Liver Disease Except for Liver Cirrhosis |
| Acronym: | -- |
| Status: | Recruiting |
| Study Results: | No Results Available |
| Results: | -- |
| Conditions: | Non-Alcoholic Fatty Liver Disease |
| Interventions: | Drug: Oltipraz|Drug: Placebos |
| Outcome Measures: | Variation of liver fat assessed|The variation in the amount of liver fat|Variation of liver fat certificate grade|Variation of NFS variation|Variation of liver elasticities and fatty acids|FIB-4|BMI|Variation of ALT, AST, ??-glutamyl transferase (GGT)|Cholesterol (total, low-density lipoprotein (LDL), high-density lipoprotein (HDL), very low-density lipoprotein (VLDL), triglyceride (TG)|Variation of Homeostatic model adjustment-insulin resistance (HOMA-IR) index|Waist circumference |
| Sponsor/Collaborators: | PharmaKing |
| Gender: | All |
| Age: | 19 Years to 75 Years ?? (Adult, Older Adult) |
| Phases: | Phase 3 |
| Enrollment: | 144 |
| Study Type: | Interventional |
| Study Designs: | Allocation: Randomized|Intervention Model: Parallel Assignment|Masking: Single (Participant)|Primary Purpose: Treatment |
| Start Date: | November 15, 2019 |
| Completion Date: | October 2021 |
| Results First Posted: | -- |
| Last Update Posted: | August 21, 2020 |
| Locations: | Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do, Korea, Republic of|The Catholic University of Korea, Uijeongbu ST. Mary's Hospital, Uijeongbu-si, Gyeonggi-do, Korea, Republic of|Inha University Hospital, Incheon, Junggu, Korea, Republic of|Soonchunhyang University Bucheon Hospital, Bucheon, Korea, Republic of|Dong-A University Hospital, Busan, Korea, Republic of|Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of|Kunyang University Hospital, Daejeon, Korea, Republic of|Gangneung Asan Medical Center, Gangneung-si, Korea, Republic of|NHUS Ilsan Hospital, Goyang-si, Korea, Republic of|Seoul National University Hospital, Seoul, Korea, Republic of|Boramae Hospital, Seoul, Korea, Republic of|Chung-Ang University Hosptial, Seoul, Korea, Republic of|Hallym University Gangnam Sungsim Hospital, Seoul, Korea, Republic of|Hanyang University Hospital, Seoul, Korea, Republic of|Severance Hospital, Seoul, Korea, Republic of|Soonchunhyang University Seoul Hospital, Seoul, Korea, Republic of|Yonsei University Gangnam Severance Hospital, Seoul, Korea, Republic of|Ajou University School of Medicine, Suwon, Korea, Republic of|Wonju Severance Christian Hospital, Wanju, Korea, Republic of |
| URL: | https://ClinicalTrials.gov/show/NCT04142749 |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| D256 | Oltipraz | Chemical drug | DB12539 | -- | Anticancer agent; antiviral | Under clinical trials | Details |
| D080 | Citrulline | Chemical drug | DB00155 | -- | -- | Under clinical trials | Details |
| D182 | Insulin | Biological drug | DB00030 | INSR agonist; CPE modulator&product of | -- | Under clinical trials | Details |