| Trial ID: | L0571 |
| Source ID: | IRCT2016061516123N8
|
| Associated Drug: |
Melatonin
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| Title: |
Evaluation of the effects of Melatonin Supplementation on Hepatic Enzymes, Inflammatory Factors, Lipid profile, blood glucose, Insulin Sensitivity, and Hepatic Steatosis grade in patients with Non-alcoholic fatty liver disease
|
| Acronym: |
--
|
| Status: |
Recruiting
|
| Study Results: |
No Results Available
|
| Results: |
--
|
| Conditions: |
Nonalcoholic fatty liver disease (NAFLD). <br>nonalcoholic steatohepatitis;nonalcoholic steatohepatitis
|
| Interventions: |
Intervention 1: Melatonin, Tab 5 mg, once a dayT 3 months. Intervention 2: Placebo, 5 mg, 3 months.;Treatment - Other;Placebo;Melatonin, Tab 5 mg, once a dayT 3 months;Placebo, 5 mg, 3 months
|
| Outcome Measures: |
Alanine transaminase. Timepoint: before intervention and after 3 months. Method of measurement: seum level.;Aspartate transaminase. Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Tumor necrosis factor alpha. Timepoint: before intervention and after 3 months. Method of measurement: serum level.;High sensitive C reactive protein. Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Triglyceride. Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Total cholesterol. Timepoint: before intervention and after 3 months. Method of measurement: serum level.;Low density lipoprotein (LDL). Timepoint: before intervention and after 3 months. Method of measurement: serum level.;High density lipoprotein (HDL). Timepoint: before intervention and after 3 months. Method of measurement: serum level.Sleep quality. Timepoint: before and 3 months after intervention. Method of measurement: Pittsburgh sleep quality index questionnaire.
|
| Sponsor/Collaborators: |
Vice Chancellor for Research and Technology, Ahvaz Jundishapur University of Medical Sciences
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| Gender: |
All
|
| Age: |
18 years60 years
|
| Phases: |
Not applicable
|
| Enrollment: |
50
|
| Study Type: |
interventional
|
| Study Designs: |
Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment.
|
| Start Date: |
28/08/2016
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| Completion Date: |
--
|
| Results First Posted: |
--
|
| Last Update Posted: |
22 February 2018
|
| Locations: |
Iran (Islamic Republic of)
|
| URL: |
http://en.irct.ir/trial/15186
|
